Should I continue to put them together?

[TheReptileEnthusiast]

I have been placing my normal female and male spider pythons together, for 2 days solid they have been locking up. I separated them after they seemed to be rather exhausted so I fed the male, the female wanted nothing. Now I place the male in there again and they don't seem to want anything to do with one another, my question is are they done? Should I call it quits with this pair now?

Just want to make certain they weren't locked when you seperated them. This can severely damage the hemipenes.
As far as pairing them again, yes, continue to pair them up regularly. Let them rest between pairings and try and keep them eating. I have males that never go off feed and can breed non stop, but some need to be shut down if they go off feed and lose weight. The females usually start feeding heavily when they are developing eggs, but go off feed when the eggs get larger and they are close to laying.