I think this strongly depends on what you consider a "issue"
This is my own personal opinion:
"Beauty" issues
I only add Ball Pythons to my breeding program that I believe a good visual examples of their genetics. If I do not think the animal is a good visual example of its morph do I think it should never be bred by anyone? No, just not by me. Some other BP breeder may like the look of it and decided to add it to their program.
Health issues
I believe Ball Pythons who are born too deformed to live a comfortable life should be humanly euthanized. By this I mean deformities that prevent the animal from properly eating, may be causing the animal pain or prevent the animal from properly moving (i.e. Spinal deformities). I DO NOT believe the Spider wobble is ever cause to euthanize an animal unless it is so sever that the animal cannot feed (which I've never heard of a case that severe) Any Ball Python with a Spider gene that has a wobble should be given a chance to grow out of the wobble (as most I've seen do) if the animal does not grow out of it, it should be kept as only a pet.
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