Use a polycarbonate (you can buy small sheets at home depot) instead of plexiglass, the stuff is 200x stronger than plexi and much more heat resistant. They were like 15-20$ bucks for a 24"x12". I have had 100w heatlamps 3-4 inches above ventilated polycarbonate for years. I drilled a few rows of half-inch holes through it (I don't know how big your snake is). If you watch my Bredli video in my sig at some point you get a brief shot of the top of my setup, 3:05.
The 100w infrared occasionally buckles the one section up (very slightly) but it is perfectly fine. The 100w daybulb doesn't cause any buckling at all.
Do not put a basking light on top of this though.