When you first get your snake home, leave him/her be for about a week. Moving to a new home can be stressful for a snake. Just as it for us humans! Giving him/her a week to settle in to its new home, will help tremendously. Stress can cause a lot of things to go wrong with caring for snakes, such as aggression, not eating, and bad sheds.
After about a week you can start regularly handling your BP, except for 2 to 3 days after feeding.

Good luck!