Yes tips would be reading body language when you handle them. It's so funny because I was just going to start a thread with this same topic. I just got a female butter enchi and she is an absolute fiery pissy you know what. She strikes at anything. While I have other babies that just are chill as chill can be, body relaxed when you hold them, never strike. Although I do like my snakes with a little edge, I think it's more natural when they act that way. Also, yes I firmly believe a snake will tame out the more you hold them. They will get more and more comfortable. Good luck in your search.