We have all our animals set up to be able to take care of themselfs for atleast a week without anyone checking. So with someone checking on them and they miss something I know they are okay. We only have reptiles and rats/mice so it's easy for us.
Since you are only going to be gone for a couple days and I'm sure you have everything set up easy for your friends to take care of them don't worry. They will be fine and you'll be back before you know it.
Merry Christmas and enjoy your tirp!!!!