When I used to breed snakes, I had a few (bull snakes, a boa female, and a couple of kings) that I swore were just evil. No matter what I did, they never calmed down. I just usually expected a bite and if it never came, well then, that was a good day.
Other than that, I got bit by babies like everybody else said. I once got bit by a baby who wasn't even out of the egg yet. I reached over him and pow, the baby is attached and I'm stuck not moving until he decided to let go. It felt like forever. He ended up being one of the most beautiful, calmest snakes I had (a honduran milk)