About the bolded: How certain are you about this supposedly heavy inbreeding early on with spiders? Have you seen documentation of this, or is this just hearsay? I haven't seen any evidence to suggest spiders were more heavily inbred than other mutations, especially considering they reproduce in the first generation. Sure, maybe two or three generations when they were still trying to find a super form, but that doesn't really constitute heavy inbreeding when compared to most recessive mutations. Simple logic would tell me the exact opposite would have been more likely, and the original spider male would have been bred much more to normal females and other mutations than to his spider daughters.