When to change bedding...

[RichsBallPythons]

Momma rat had some babies last night @ 9pm. About 19 total, her cage Looks like a bomb went off in it. Bloody news paper, aspen bedding the whole 9 yards. She is still housed with the male. I do have a spare tank to put her and babies in but I guess my question is how soon can I change her bedding? Should I do a partial change to get most of the soiled stuff out? I checked the babies today she had 2 dead ones looked like the had been trampled on that I removed and I fed one live to my beardie. But question in point is when should I change the bedding...
Thanks in advance,
Jeff

I do nothing special for mothers giving birth. i just clean on normal 5 day schedule. My females dont mind me messing with them day of giving birth. If i notice birthing during cleaning i come back to that tub later.