azmodane-if you were talking to me....
I prekill one and give it to her (shake it in her cage for movement) wait till she finishes eating it, then kill the other (and repeat the "shaking" thing...) She strikes and constricts them for a few minutes as if they were alive before she eats them.
I don't like the idea of suffocating them, (many on this forum have different opinions on humane ways to kill mice,) I prefer the quick-blow-to-the-head way so they don't know it's coming and it's quick-so no, I don't use CO2 esp since I'm prekilling in "bulk".