If she is running away she is not receptive and will fight him. He will continue to try to mate with her.
Have you quarantined her? How much does she weigh?
Introduce them when she is ovulating, she should be receptive then. Biting is a part of the male's behavior when he is trying to breed a female.
You should keep them separate except for when you introduce them to breed. Let them do the deed, then separate them again.