When we use Carefresh in our snakes' tanks, we always spend about 15 minutes "shaking" and agitating it in the tank with a fan on it while one of us holds the snake so we get dust out. I checked on her yesterday and she was fine, no hissing or anything. I plan on checking on her again in the next couple days though. We ended up with a package with new labeling and a package with old labeling, the newer pack had significantly less dust than the old pack. When we were standing in front of the Carefresh my first thought was "I'll die if I give Zoey or Sparks a RI." But we've used it with success in the past with the "dusting" method.