snakes are the best pets to have for just this reason. you CAN leave them for a couple of days as long as they have enough water. think of them in the wild... do they always have fresh water served up for them every day.? Yes they can roam to fresh water, but sometimes during dry seasons, that isn`t an option. Your snake will be just fine. make sure there is plenty of water.... If your snake likes baths, give it a bath. they tend to drink plenty of water in the tub to last for a couple days. I am not an expert, but I have owned snakews for around 7 or so years, so I would say you are pretty safe.