Air flow is always an issue, especially this time of year when it starts heating up. My rat room is completely enclosed but I have a duct bringing in air from the outside and a heavy duty exhaust fan sucking the air out of the room and exhausting it outside 24/7 I've had my fan fail on me twice when I blew a circuit and both times I had massive loss of life within only a few hours. The air turned so bad so quickly that I nearly passed out walking into the room. If you can hook up an exhaust fan to the outside that would probably help a lot. You can find them online pretty easily at sites that sells hydroponic supplies.
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