No once you get approved to ship "live harmless reptiles" via Fed-Ex priority overnight, then as long as your account stays active then your good to go.
It is a bit of a process to get the account setup..get with you account rep. Sign and return all the papers, setup and send your test package, get all of the Test info back and get your certified approval number..
If everything goes smooth it took us about 2 months to get everything done from start to finish..