Like others said, a lump will do no harm. I like seeing my girl with a lump in her, actually. It's definite satisfaction. Just make sure your BP is sitting on the warm side so it doesn't take too long for that large prey item to break down in his stomach, and possibly turn rancid.

However, like others didn't point out (and I don't mean to start an argument here), but if you went on vacation for 3 weeks, who did you have to drop in every few days to check water bowls and spot clean for you? If you had someone to do that, they could have easily fed the snake for you as well. Provided they didn't mind mice.