I just wanted to clarify something for you with regards to this. The T+ and T- are just the different classifications of albinism with regards to the mechanism which causes the phenotype. The mutation causing T- albinism (the more common form of albinism) turns off the production of the enzyme tyrosinase. Because tyrosinase is responsible for manufacturing melanin, the animal lacks black or brown pigment. The mutation causing T+ (or caramel) albinism results in mutated tyrosinase enzymes, which fail to produce melanin. Because of this, the animal has no black or brown pigment. However, because tyrosinase is still present in the animal's skin, the animal takes on a sort of bronze or caramel colour in the places which would have black or brown colouration on the wild-type. I believe the colour of tyrosinase is attributed to the presence of copper in its active site.Originally Posted by Bruceweb
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