I advise gloves. My female tagged me quite well and ended up leaving a tooth in my finger for about a week (To be fair, she was ging into shed). Wasn't too fun when the tooth started worming its way out from the injury healing. Mine was a breeder and wasn't handled very muchbefore I bought her. So before I get her out of the tank, I get a long pair of feeding tongs and run it down her body to let her know I'm going to handle her. When she stops jumping, I pick her up. This method seems to work well since she hasn't tried to strike at me since.