There is no information that suggests breeding spider x spider will result in more of a neurological disorder in offspring than just breeding spider x normal. People incorrectly assume ball python genetics are like canine genetics. In dogs, there are many different genes at work to produce each breed, and inbreeding can easily result in disorders simply because they have already been inbred for thousands of years to produce the different look of each breed. Spider ball pythons however, are just caused by one mutation. That particular mutation just happens to also cause spiders to wobble.

Now, as far as my take on the way you are thinking about going, you might consider buying an orange hypo and a spider het hypo as your breeding pair if you are looking to make honeybees. You'd spend more money this way, but it'd save you 2 or 3 years, and you wouldn't have to deal with possible hets this way. Hypo x spider would give you 1:2 spider het hypo, and 1:2 normal het hypo. hypo x spider het hypo, however, would give you 1:4 honeybee, 1:4 spider het hypo, 1:4 hypo, and 1:4 het hypo