Ok...I got my book out and did some research for you. This is what I found....It could indicate a period of heavy breeding (not sure if you are breeding)....or a possible bacterial or protozoan infection.
Either of the last two would certainly require a immediate trip to the vet.
I hope that this helps! Also if you happen to have a sample of poo....I would take that in as well. Put it in the fridge until you can see the vet.
As far as the wrinkles.....is your snake getting ready to shed? If it is an infection it could be causing her to become dehydrated as well.
Ok...well I hope that helps...