Pick a day that you can spend a couple hours doing this...
Start in one specific room that is easy to search. Search it thoroughly, then seal it off. I mean tape around the door edges and everything. Work from there until you have narrowed down the space the little guy could be in.
I know this sounds kinda obvious, but when I lost my baby corn I found myself searching frantically from room to room and back again, and wasting my energy in the process.
Another thing to try is to leave out bait (whatever you normally feed it) and very nearby leave your snake's favourite hide and some mild heat source. Hopefully it he/she will eat, and go to the nearest warmth to digest. Viola, snake
Good luck!