I also caught the RI fairly early--and I mean really paranoid neurotic early--the day he started clicking and had a couple wheezes (and a bit of bubbles in the mouth,) off to the vet the next day. After 2 shots of Fortaz, he's stopped clicking and wheezing altogether (but just to be safe I think my vet will continue it on a one month treatment) so it may depend on a combination of how severe the RI is and how well the snake reacts to the antibiotic.

Of course, he's starting to hiss at me (which he hasn't done since the day he came home with me) every time I open the tub so that may be an unfortunate side effect.

To be fair, I'd probably hiss at the crazy limbed giant that hurts me every time my house's roof is torn off.