I believe the following two statistics are accurate:
45 thousand americans die in car crashes every year.
12 people TOTAL in the past ~20 years have died from captive reptiles. This includes venomous reptiles and salmonella infections. And unless I'm mistaken, all of those people have been the owners of the animals or residents where the animal resided.
Now the number of people that drive far outweighs the number of dangerous reptiles kept privately, but I still believe that statistically, driving is far more dangerous than keeping reptiles with the ability to kill humans.
The big issue for me is that for the most part, keeping dangerous reptiles is not dangerous to the community at large. The same cannot be said for driving, or even firearms. When you drive, you put thousands of people at risk. Just think of all the pedestrians and all the other cars around.
You don't need a license to operate vehicles on private property, or carry firearms on private property either.
The laws regarding purchasing firearms are to fight crime. We already have laws regarding purchasing reptiles and preventing reptile-related crime. The thing is that reptile-related crime is usually related to illegal importation/exportation, which is directly related to conserving wildlife.
Until dangerous reptiles start attacking and killing random people in public, I'm not going to be in favor of legislation based on the argument of safety.