Quote Originally Posted by RandyRemington View Post
Not having any piebalds much less having raised a large number of piebalds for years I really can't say one way or the other.

I can report that I have lost two unrelated POSSIBLE het piebalds years apart to chronic constipation (and no non piebald project animals to this). The first one after soaking didn't work I took her into my vet who massaged a large bowl movement out. She then ate again but the problem came back shortly and she died. I took her in to the vet who dissected her and said that her intestine was thin and non muscular similar to a known genetic condition in cats called Megacolin. Doing some research and it sounds like its piebald cats that tend to develop this condition.

So, very circumstantial, especially given that I don't know if either ball even was het piebald. I’ve got lots of other possible het piebalds that I think are very likely het pieds that I’ve had for years without this problem. I've posted several times asking about constipation seen with the piebald gene and NOONE has come forward with any similar accounts of problems with homozygous piebald ball pythons.
Megacolon is also a big problem in breeding high white rats as well.

An animal with megacolon has serious issues passing feces and fails to thrive and eventually dies. Anyone interested in megacolon in rats can read this article, i read it a while back and it had a ton of useful info.

http://ratguide.com/health/digestive/megacolon.php

Useful especially because a bunch of people on these forums breed their own feeders.