Yea I think using a vacuum might affect a ball python, since whenever I vacuum in my room they try to feed it, they usually miss the first 2 tries, then finally grabs onto it. It usually depends on the snake also. Some could not be affected while others go off-feed.Hope that helps.
I'm confused by this statement. Your snake tries to "feed" your vacuum?? Why are you putting a vacuum that close to your snake??