I have never used reptile relief, sorry. But in the past I have used olive oil. Just rub all over the snake like you are putting sun tan lotion on. Let the snake sit in another cage, box or what have you for atleast 1 hr. clean out cage and all cage stuff with a water bleach mix. Let air dry for the hour. Wash snake with baby soap, I use baby soap when washing all my snakes. Repeat procedure again in a few days if you happen to see any more mites. It usually works great the first time. Now other people I'm sure will have other ideas but this has worked great for me and for other people that I have told. Hope this helps. I have never had mite problems with any of my dragon's.