I Second Hoax...............
Your BP will let you know whats up.......each snake will have limits.....overall tolerance to handling....etc etc....your snake will give you feedback thru your hands, by it's movement, feeding performance etc....know your snake and you will know its day to day...week to week limits. There needs to be a time awareness though no matter how good they do for the simple fact of temperature control. If you are handling for 2 hours outside their tub in a 70 degree room this could be going against their thermoregulating desire or needs.
I still have 1 out of 10 that just as soon bite my hand to shooooo me away each time I go to clean, spotcheck, feed, handle or what have you.
From the beginning she would strike 5-8 times each time I would move my hand into the tub to clean, handle or what have you. She gets 5-10 minutes everyday and she is just getting to where she will relax in my hand and move around. But she still will try to keep me from getting her out of the tub each time. She still feeds like a champ and this is why I am religous about continuing to handle each day except for post feed. She is slowly but surely changing but she is much like my wife. It has taken her 8 years to be trained to do all the work in the houselawl jk....
"checks to make sure she is not behind me"