my 6ft argentine boa keeps hissing at me whenever i go to touch him in or take him out of his cage. we acquired him about 2 weeks ago we gave him a week to get comfy in his new house (and he shed fairly cleanly) then we fed him yesterday. its strange because he doesnt strike, he just pulls his head back a little cracks a smile (ok its not really a smile) and lets out this deep gutteral hiss like he wants to kill me and then if i stop touching him he stops or if i get brave enough to pick his head up and go from there.
why does he do this?
also do you think that handling him as often as possible will make him more comfortable or make him more angry?

i realize i cant snuggle him but i would like to hold him and let him get more comfortable around me and my boyfriend. and get us not as scared of him.

thank you