when I handle him I don't have him in my hands. He is either on my chest or lap and I have a blanket over us. He falls asleep frequently there and if he starts moving heading back to his tank I pick him up then and return him. He does not show any signs of stress which is why I'm being very watchful for any possible signs.
Whatever works for you then. If a ball python is still eating it's a good indicator that it's fine. I'm just saying that removing him from his secure hiding spot every day could be a big source of stress, especially for a small snake.