Probably about 10 times and all from my old corn snake. Doesn't hurt just more startling than anything. He did bite once and didn't let go tho. Swear he was trying to eat my hand lol. My ball python I've never even been struck by. Hisses every now and again when he's in shed, but apart from that for the 4-5 years I've had him I haven't seen any aggressive behavior from him.