I'd have to say no.
Some snakes will only eat live and then you are stuck trying to get rid of a snake which is no easy task.

But I understand your delema. I feed my snakes both frozen and live, I have a pair of breeder rats for that purpose. And while I get the whole circle of life thing, I still feel a little bad when I have to grab a cute little ween to feed to one of my picky eaters.