The market name for at least one of the veterinary solutions used is Beauthanasia-D. It's a bright pink liquid. It stops the heart and brain activity within seconds. Sadly we use it an average of three times a week on elderly or seriously ill patients. I can tell you its the most peaceful death I could ever imagine. Even when we do heart sticks on cats, they rarely fuss. Many times if we have concerns about the patient getting fidgety we'll give a dose of surgical anesthetic and let that take effect first. I doubt many vets approach it differently, even for reptiles. My preference if I had a very sick animal that for whatever reason I could not treat would definitely be euthanasia by injection. It never gets easier to see but it's the one of the most humane deaths.
Snakes go much, much slower and often fight it. I agree, euthanization in small mammals, dog, cats and lizards is almost instantaneous.