I've only had one completely incapacitate me, and that was because I was overworked at the time. I couldn't get out of bed for a week, and it sent me to the hospital. Normally I try to catch them early, which is what I've been doing all week. Keeps me somewhat functional, Tylenol and cola, enough so that I'm not stuck with my head under a pillow. Little movement and sound goes a long way, but even walking upstairs to use the bathroom sets my temple to THROBBING.