I don't think you should pick and choose. What's the difference if the mutation is done naturally or artificially? What if I injected a normal python embryo with the genetic material in order to get a bumble bee? Would that make it wrong? What if I manipulated the genetic material to get rid of spider wobble or caramel kinks? In the end, it's all genetic manipulation whether it is done naturally or by more advanced methods.
There will always be people out there that will refer to morph breeders as "mad scientists", but I couldn't care less. In the end, you have to decide what is morally right for you to do. However, to chastise science and scientific methods on one hand while defending your own actions because it's "natural"; you become what you criticize.