So about 10 min ago i went to pick up my 1100+ gram female pastel. I have had her for about 2 months and have held her about 20 times. I went to pick her up again tonight and she hissed at me. At first i moved away then i went back and kept touching her so she didnt think she could hiss at me to keep me away. I didnt pick her up cause i didnt want to stress her out. I did feed one of my other snakes in the bin below her. She is the only one out of the 4 snakes that i have that has to eat live. I fed a FT mouse to the male spider under her. Do u think she smelt it and thats y she hissed at me? She is the tamest out of all my snakes. The male spider hissed at me before and my male 100% albino struck at me the first time i tried to pick him up. But this female pastel has let me pick her up anytime i want.