I'm wondering what everyone's methodology/strategy is for out crossing their recessive bloodlines?

What kind of pairings would you feel comfortable with if you were dealing with a new recessive morph that has been line bred for proving out purposes?

How many generations of line breeding are you comfortable with before you start to worry about genetic deformaties?

What is the most efficient way to strengthen a recessive blood line?

Any other advice for working with recessive traits?

Thanks for the help!