Really depends on what species you are talking about... Some are really touchy, while others like Veileds and Panthers do very well in captivity. Fishers arequire a few adjustments as far as temp and humidity go compared to most captive Chameleons...but tend be a fairly successful captive species. There has been a lot of advancement in the keeping of Mellers over the last few years, as there was a major lack in solid research that had been done...But now we are seeing a lot of CB Melleri available meaning that there has been a good amount of success with them. Parsons... pfshhh... Very tough in captivity... I am still years from feeling comfortable enough to spend thousands of dollars for something that has a low captive success rate such as Parsons... Even though it is my dream to own one some day... I won't support the illegal pet trade...Therefore I probably will never own one unless CITES starts to allow them to be exported again sometime in the future.