I am really sorry to hear about this whole situation.
Any dog at any time can easily turn on each other or their handler unfortunately. It can be due to the pack order, redirected aggression (which sounds like why she went after your wife; easiest way to explain it is they go into a 'zone' and don't necessarily realize who they are attacking once in it), flooding, alphas etc... I am just speaking from personal experience and dog training.
If you are attempting to rehome or not, I would absolutely recommend keeping leashes on your girls at ALL times for atleast 6 weeks. Also keep them seperated if only one of you are home. It takes canines about 1 1/2 months to straighten out their issues with eachother and settle the pack again (usually).