Generally my cats and the snakes I've had for longer periods of time show no interest in each other. Accidents can still happen though. Once I was filling water dishes and while I was in the bathroom one of the kitties decided to jump in the open 4' x 2' Sumatran short tail cage and got bit in the head. I'd only had that snake for about a year and got him as an adult and he still thought cats smelled like food.