It just depends on their personalities...some of mine could be TV stars they love attention so much. Two of my albinos, in particular, spend more time hiding than Newt on Aliens 2.
48 hours is definitely sufficient to wait after a meal before handling. Sounds like you're doing everything right.
Don't worry about them eating the butt first, it happens. They probably pick which way to eat depending on what flavor they want to have left in their mouth on the way down...mouse snot or mouse bum! ;)
JonV