Nippy Ball Python

Yes, and it does not hurt much when you do get tagged by one. My little Bela tried biting me the instant I opened her shipping box. Nothing in the world is cuter than that site was!
But it can be a pain when they are bigger and trying to bite you. I think it usually cools down by the time they grow, though, if you regularly handle them.

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Originally Posted by Ginevive

But it can be a pain when they are bigger and trying to bite you.

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This is very true with any large python a friend of mine has a 16' Female Burmese. One day he went in her enclosure to change the water and clean up some waste. When he was cleaning I noticed that Tiny was tracking him. I told him you better get out of there. Right when he closed the door to the enclosure she struck and missed him by a matter of inches. We just figured she was cranky because she is always such a sweetheart. My point is that a cranky ball python aint too bad but a cranky 16' burmese is a snake to be reckoned with. Well we were trying to figure out why she was tracking him and then he remembered that the pants he was were sitting on top of the cage where he breeds his feeders.

I think it's pretty common for balls that have been seriously ill in some way to be nippy and/or grouchy when they're really on the road to recovery. Snyder did that, but she did calm back down after a month or two of regular handling.