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markers

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  • 04-18-2006, 02:03 AM
    blackula19
    markers
    does anyone know of a website showing pics of genetic markers? i know they aren't 100 percent, but i am curious. also what are the common marker types? thanks. ed
  • 04-18-2006, 02:13 AM
    JLC
    Re: markers
    So far as I know, the only non-visible het that anyone claims to have markers is the pied. Although I suppose one might consider the traits of a yellow-belly to be markers for a het-ivory.


    Here is a useful site that describes the sometimes hard-to-spot traits of true yellow-bellies, granites, and other morphs. It includes the marker for het-pied, but does not guarantee such observations:

    http://www.nextworldexotics.com/hg.htm

    Hope that helps ya.
  • 04-18-2006, 08:56 AM
    RandyRemington
    Re: markers
    Someone pointed out in another thread that the term "marker" indicates a separate gene that indicates the presence of the gene you are interested in.

    I'm not sure that "marker" is the best term here as it might be the pied gene it's self that is sporadically showing through in some of the hets.
  • 04-18-2006, 11:32 AM
    Adam_Wysocki
    Re: markers
    It's all cr@p ... the top three largest pied producers in the world have all publicly pointed out different so called "markers" that they each think could indicate the het pieds in a clutch of possible hets ... two totally unrelated pattern variations, and a color variation.

    If the guys/gals that see more het/possible het pieds than everyone else on the planet combined can't figure it out for going on 8 years now, how much do you really think that there is to it?

    I've been around ball pythons for a very long time and each year I hear about a different "marker" in a different mutation ... I've heard about them in possible het albinos, possible het hypos, possible het pieds, possible het clowns, possible het stripes, possible het axanthics ... blah blah blah .... If you ask me, it's just a bunch of wishful thinking.

    Markers or no markers, if you breed a 100% het to a normal ALL of the babies each have a 50/50 shot at being a het ... period. That is a reality that no one can dispute. ;)

    -adam
  • 04-18-2006, 11:43 AM
    Wild Bill
    Re: markers
    The only markers I like are "Sharpies". ;)
  • 04-18-2006, 11:46 AM
    Melicious
    Re: markers
    Quote:

    Originally Posted by Wild Bill
    The only markers I like are "Sharpies". ;)

    And they come in SO many colors!
  • 04-18-2006, 01:06 PM
    Mendel's Balls
    Re: markers
    Quote:

    Originally Posted by RandyRemington
    Someone pointed out in another thread that the term "marker" indicates a separate gene that indicates the presence of the gene you are interested in.

    I'm not sure that "marker" is the best term here as it might be the pied gene it's self that is sporadically showing through in some of the hets.

    A genetic marker is indeed another gene or DNA sequence that is associated with another gene. I doubt anyone has created a linkage map for ball python genes. I know no one has created a physical genetic map since not one reptile geneome has been sequenced yet.

    People on here tend to use the term "marker" as if the heterozygote genotype itself shows through in the animial's phenotype. This is more like an example of incomplete dominance or penetrance.

    I am new to the ball python world but I wouldnt put to much faith in the these so called "het markers". For example, if I was breeding pied I wouldnt "throw away" those 66% or 50% possible het pieds that lacked a het maker.

    I checked the site above and looked at the het marker guide for pied and maybe its just my untrained ball python eyes but I wasnt very convinced......animial looked pretty much like a wild-type to me. In one of the pics of the same guide the author said the animial was a "also a ringer" and I can maybe see where he gets that but I think he's stretching there.....so I am inclined to say all of this is wishful thinking like Adam said.

    The author of the above site lists that here are the phenotypic markers for het pied

    1. Black striping down BOTH sides
    2. Clear belly between the stripes

    Before this he stipulates that most of them with this marker turn out not to be het and instead complete normals.

    Lets assume there is something to this phenotypic marker ....I'll offer another explanation of why it might be "seen" in het pied..... .maybe it's caused by another gene that is on the same chromosome for the pied gene.......Then it would fit the definatiion of a genetic marker. Even then though it usefulness for differentiating the genotype of 50%/66% het from homozygous complete normals would only be as good as how close it is on the chromosome to the pied gene. This is because even linked genes undergo recombination through chromosome cross-over in meiosis.

    See http://www2.dpi.qld.gov.au/beef/2244.html

    See the section titled "Exploiting Major genes with Genetic Markers"

    But before we start take any explanation seriously though.....I think someone has to show definatively it really is significant, not just wishful thinking....
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