Jolly Suddenly Being Skittish

So my fiance and I have been enjoying our new ball python, Jolly, for the last month. He's always been very sweet, curious and easy going about being handled. We recently moved to a new apartment, however, and since he's been acting weird. He wasn't out of his environment for more than an hour. We timed the move around his regular feeding schedule so not to disturb his digesting. I thought we did everything right. Since he's been scared of everything, behaving like he can't see almost. He missed his last meal at least six times trying to strike it and typically he eats two mice, this last time he only ate one. (Although worrisome, I didn't have my blow-dryer since it was lost in boxes but do have it now so when we feed him again in a few days we'll see if the warmth helps.) Our concern comes from his behavior when held. He's super jumpy and twitchy, retracting at every little noise or action.

For example, I went to change his water and he was nestled nearby. Normally he doesn't care, is even curious, but this time he just recoiled and snapped back. He didn't move until I was done and then he just retreated into his hide, very defensive. I feel bad because I assumed I scared him but it's been every little thing. Spraying the tank, changing bedding, checking temps, going to hold him... anything. We held him last night and his breathing was very erratic, anxious almost and it took him a long time to calm down. We did have to get him a new hide because the old one was far too small and he kept getting stuck.

We've had him about four weeks and he hasn't shed. Not sure when his last one was with the other owner but don't notice any signs.

Give him some time to acclimate to his new environment sounds like he is stressed. Check your enclosure temps and humidity. :)

It does seem like the humidity is higher here. I haven't had to keep it up since we moved in, since we're on a subfloor. It stays at about 65 and I am unsure how or if I should lower it.

I wouldn't handle Jolly for a week or two. Let him get a couple feeding under his belts in his new environment.
I'm still new at being a snake owner myself but this little guys need to be happy and stress free. A move is definitely a stressful event for these animals.
After a week or two I'm sure you will see a change in your guy.