Gut Loading?

So I'm curious. With other (non-snake) reptiles that I've owned, gutloading feeders was a big part of nutrition. Healthy feeder = healthy reptile. Is the same idea true for rodents and ball pythons? Personally, I'd like to feed rodents that I've owned, fed well, and ensured are healthy-- but does that make a difference, say as opposed to frozen feeders?

There is no need to "gut load" feeder rats or mice, a healthy feeder live or f/t is all that is necessary.