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Homozygous Dominant Genes

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  • 11-14-2011, 01:19 AM
    rigomez4
    Homozygous Dominant Genes
    I have read that some people believe homozygous dominant genes may result in a lethal gene combination. All I have read use a spider x spider cross (homozygous spider) as an example. I was wondering if it holds true for,

    pinstripe x pinstripe (homozygous pinstripe)
    spinner (spider/pinstripe) x spider (homozygous spider)
    spinner (spider/pinstripe) x pinstripe (homozygous pinstripe)

    I just have not read anything on the potential lethal gene in these combinations. Thanks.
  • 11-14-2011, 01:23 AM
    Jessica Loesch
    No one knows for sure.
  • 11-14-2011, 02:20 AM
    paulh
    Re: Homozygous Dominant Genes
    Homozygous codominant mutant genes MAY result in a lethal gene combination. Homozygous recessive mutant genes also MAY result in a lethal gene combination. They are not required to result in a lethal gene combination.

    A lethal dominant gene is lethal when there is one mutant gene in the gene pair. Such mutant genes do not survive to a second generation except in rare circumstances.

    As far as I know, homozygous pinstripe is not lethal.

    As Jessica wrote, nobody is certain about homozygous spider. Nobody has ever claimed to have one. All known spiders are heterozygous -- they have a spider mutant gene paired with a normal gene.

    A spinner has two gene pairs with mutant genes -- a spider mutant gene paired with a normal mutant gene and a pinstripe mutant gene paired with a normal gene. I would expect it is possible to breed a snake with two pinstripe genes and a spider mutant gene paired with a normal gene.

    Examples of lethal codominant mutant genes: jaguar in carpet pythons, crested in canaries, sickle cell in humans.

    An example of a lethal recessive mutant gene: jaundice in the lab mouse.
  • 11-14-2011, 03:37 AM
    rigomez4
    Re: Homozygous Dominant Genes
    Thanks.
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