Your going to have to give us more info.. What size is the snake? WWhat size is the enclosure? How many hides do you have? Whats the temps on warm side and cool side? Whats the humidity? What size prey are you trying to feed it? Is it frozen or live prey? We need info...
My suggestion would be for you to take him/her to the vet. There they can diagnose any causes of the hunger strike as well as administer probable cures as well. They can also force/assist feed your ball python and teach you how to as well, assuming that this drastic of a measure is truly needed.
You should also double check your cage setup to ensure you have the proper temperatures and humidity levels. Also, because you did not post any pictures or a description of your snakes cage, make sure you are providing water and at least one hide box.
Pictures always help when asking for this kind of help, of both the snake and the cage. The more details that you can provide the better.