The only times I get nervous about being bitten by our BP Snickers are when her eyes are clouded over before a shed. My boyfriend and I don't even want to handle her during that time but we do for maybe 30 seconds tops while both of her hides are checked for defecation and urates. Snickers uses ANYWHERE in her enclosure as a toilet(in her hides, outside of her hides, or in her water dish)
Snickers has never bit either of us or even hissed at us but when her eyes are clouded over it's pretty obvious by her body language that she doesn't want to be handled and likewise we don't even want to handle her.....
But we feel like we have to because we check her tank for poop and urates every night....
Is that necessary during an impending shed or not? We don't want to be bitten or make Snickers freaked out but we don't want her curled up in one of her hides right next to one of her turds either.