I rescued a juvenile (300g) piebald ball python a few months ago. They were giving him away on craigslist because it had a respiratory infection and they didn't want to deal with it. I took him to the vet ASAP and the doctor prescribed a months worth of injectable antibiotics (10 shots). I thought it did the trick but in about two weeks I noticed signs of a RI and back to vet again. I am now on my second month of oral antibiotics (bytril) every other day for the past 6 weeks with two more weeks to go he sounds a little bit better but he definitely still has an infection. I believe he's going to need at least another months worth of antibiotics but maybe more.

Has anyone else ever had a stubborn RI that took a long time to cure? I take meticulous care of my snakes and have never had a RI before.

He's still eating normally, shedding in one piece, and is gaining weight each month.

Any advice would be greatly appreciated.